107449 <common-name>Encenicline</common-name> <description>Encenicline is an organic compound with the formula C16H17ClN2OS and an average molecular weight of 320.84 g/mol. Encenicline belongs to the 1-benzothiophenes, a subclass of benzothiophenes within the organic compounds. It is classified as an organoheterocyclic compound. Regarding its biological activity, encenicline acts as a partial agonist of the neuronal acetylcholine receptor subunit alpha-7 (CHRNA7).</description> <cas>550999-75-2</cas> <pubchem-id>46196517</pubchem-id> <chemical-formula>C16H17ClN2OS</chemical-formula> <weight>320.8</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T13:52:51Z</created-at> <updated-at type="dateTime">2026-08-19T15:35:49Z</updated-at> <interacting-proteins nil="true"/> <wikipedia 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<structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM103342</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00073068</susdat-id> <iupac>N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Benzothiophenes</klass> <subklass>1-benzothiophenes</subklass> <paper-count type="integer">199</paper-count> <sync-id>CED0015293</sync-id> <structure-inchikey>SSRDSYXGYPJKRR-ZDUSSCGKSA-N</structure-inchikey> <structure-fingerprint>2000000000000000004000000100000002000000300000000000000000000000800000000000000000002000010000000100000000000000002000000000010000008400020400000000000000020080010000000000000401000000000000000010000000000000000100000000000020100000000020000000000100001000000000001800000000000000080040000000000000000000000000000000000000004001000000000080000100000000000000000408000000000000000000000040000000000000000000000000010000000000000040200000000000000000000000001000040000000000400000000000000000000000000000000</structure-fingerprint> 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