107364 <common-name>4-Amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboximidic acid</common-name> <description>4-Amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboximidic acid is an organic compound with the formula C20H22N4O3 and an average molecular weight of 366.42 g/mol. 4-Amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboximidic acid belongs to the benzodiazines, a subclass of diazanaphthalenes within the organic compounds. In terms of biological activity, it acts as a modulator of the Gamma-aminobutyric acid receptor subunit alpha-3 (GABRA3) protein target.</description> <cas>942436-93-3</cas> <pubchem-id>23630026</pubchem-id> <chemical-formula>C20H22N4O3</chemical-formula> <weight>366.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T13:49:14Z</created-at> <updated-at type="dateTime">2026-08-20T05:41:03Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB12210</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CCCN=C(O)C1=C(N)C2=CC=CC(C3=C(OC)C=CC(OC)=C3)=C2N=N1</moldb-smiles> <moldb-formula>C20H22N4O3</moldb-formula> <moldb-inchi>InChI=1S/C20H22N4O3/c1-4-10-22-20(25)19-17(21)14-7-5-6-13(18(14)23-24-19)15-11-12(26-2)8-9-16(15)27-3/h5-9,11H,4,10H2,1-3H3,(H2,21,23)(H,22,25)</moldb-inchi> <moldb-inchikey>NVWCZRPXYVDQEE-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">366.421</moldb-average-mass> <moldb-mono-mass type="decimal">366.1691906</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>2.64</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM103257</chemdb-id> <dsstox-id>DTXSID60915944</dsstox-id> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00072940</susdat-id> <iupac>4-amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Diazanaphthalenes</klass> <subklass>Benzodiazines</subklass> <paper-count type="integer">0</paper-count> <sync-id>CED0118873</sync-id> <structure-inchikey>NVWCZRPXYVDQEE-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>820200000000000080000100000000000000000200400004100002000000200000009000002004000000000000000000000000200000000000000000000000000000000000000000000000000100020204000000000000040020010000002040000000100000040000000000000000000080000000000001000040000000800000000000000000081000400000000000000000000000000000000000000200040000080000000000000000004000100000000000000080000008040000000000000000000000000000000000000800008280000000000800000002000000000040000000000000000000000028000000000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ������������������������€���`�������`�������`�������(�������(�������h�������@(������@(�������h�������@(������@h�������@h�������@h�������@(������@(������@(�������(�������`������@h�������@h�������@(�������(�������`������@h�������@(������@(������@(�����������������(��� �� ��h��� � h� h� �h���h�� h� � ��h��� �����h���h���h��� �����h� �h���h���h���h�� h���h�B��������� �� �� � �����������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:42:20Z</structure-indexed-at> </compound>