104794 <common-name>Orteronel</common-name> <description>Orteronel is an organic compound with the formula C18H17N3O2 and an average molecular weight of 307.35 g/mol. Orteronel belongs to the naphthalenecarboxylic acids and derivatives, a subclass of naphthalenes within the organic compounds. In terms of its chemical classification, it is further categorized as a benzenoid. This compound has been identified in or released from one recorded source, specifically electric hearing aids used in electrical and electronic equipment. Biologically, it acts as a modulator of the protein target Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1).</description> <cas>566939-85-3</cas> <pubchem-id>9796590</pubchem-id> <chemical-formula>C18H17N3O2</chemical-formula> <weight>307.3</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T11:52:33Z</created-at> <updated-at type="dateTime">2026-08-19T23:38:17Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> 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nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM100687</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00069633</susdat-id> <iupac>6-[(7S)-7-hydroxy-5H,6H,7H-pyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Benzenoids</superklass> <klass>Naphthalenes</klass> <subklass>Naphthalenecarboxylic acids and derivatives</subklass> <paper-count type="integer">433</paper-count> <sync-id>CED0011699</sync-id> <structure-inchikey>OZPFIJIOIVJZMN-SFHVURJKSA-N</structure-inchikey> <structure-fingerprint>100000000000000000000000000000000000000010000000000000000000000000000020000040000000200000000000000000000000000a00000000020000000c0000000004000000000000200000000000000000000000000000000000000100000000000000001000000000000229000000000000000000000000000000480000000000000000008000a0230000000000000000000000000000000000000000000000000000084000000000020200000000008000000040000100020000000000021000000000000000000000004000000000000200000000000000000000000001004040000000000400000002800001000040000000000000</structure-fingerprint> 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