104542 <common-name>Mavoglurant</common-name> <description>Mavoglurant is an organic compound with the formula C19H23NO3 and an average molecular weight of 313.40 g/mol. Mavoglurant belongs to the indoles and derivatives, a class of organoheterocyclic compounds within the organic compounds. Regarding its pharmacological activity, the compound is recorded as a modulator of the protein target Metabotropic glutamate receptor 5 (GRM5).</description> <cas>543906-09-8</cas> <pubchem-id>9926832</pubchem-id> <chemical-formula>C19H23NO3</chemical-formula> <weight>313.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T11:40:25Z</created-at> <updated-at type="dateTime">2026-08-20T03:45:54Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB13004</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>COC(=O)N1CC[C@@H]2[C@H]1CCC[C@@]2(O)C#CC1=CC=CC(C)=C1</moldb-smiles> <moldb-formula>C19H23NO3</moldb-formula> <moldb-inchi>InChI=1S/C19H23NO3/c1-14-5-3-6-15(13-14)8-11-19(22)10-4-7-17-16(19)9-12-20(17)18(21)23-2/h3,5-6,13,16-17,22H,4,7,9-10,12H2,1-2H3/t16-,17-,19-/m1/s1</moldb-inchi> <moldb-inchikey>ZFPZEYHRWGMJCV-ZHALLVOQSA-N</moldb-inchikey> <moldb-average-mass type="decimal">313.397</moldb-average-mass> <moldb-mono-mass type="decimal">313.1677936</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>3.02</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM100435</chemdb-id> <dsstox-id>DTXSID30202777</dsstox-id> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00069300</susdat-id> <iupac>methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-octahydro-1H-indole-1-carboxylate</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Indoles and derivatives</klass> <subklass nil="true"/> <paper-count type="integer">422</paper-count> <sync-id>CED0011812</sync-id> <structure-inchikey>ZFPZEYHRWGMJCV-ZHALLVOQSA-N</structure-inchikey> <structure-fingerprint>200000000000000020000000000000000000000000000000020204000000002000000000000000000000000000400000002000000000000000000000100000000000000000040000000000000200000200001000000000000000000000000000100000000400000001000000000000201000000000000000000041008010003484000008000000000000000a0200000000000008080000000080000000000000004000000000000080000000000000000000000008000000000000000080000000000000100002000000001000000400000002002000200000000000000000100040000000040000000000400000000000000000000001000000000</structure-fingerprint> 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