103728 <common-name>4-(2,4-Dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine</common-name> <description>4-(2,4-Dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine is an organic compound with the formula C9H10N4S and an average molecular weight of 206.27 g/mol. 4-(2,4-Dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine belongs to the thiazoles, a subclass of azoles within the organic compounds. This organoheterocyclic compound has been found in or released from two recorded sources, specifically electrical and electronic equipment including antennas and amplifiers. In terms of biological activity, the compound is associated with two recorded protein targets. It acts as an inhibitor of Cyclin-dependent kinase 2 (CDK2) and Cyclin-A2 (CCNA2).</description> <cas nil="true"/> <pubchem-id>447956</pubchem-id> <chemical-formula>C9H10N4S</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T10:52:46Z</created-at> <updated-at type="dateTime">2026-04-13T21:20:24Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB02091</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CC1=NC(C)=C(S1)C1=NC(N)=NC=C1</moldb-smiles> <moldb-formula>C9H10N4S</moldb-formula> <moldb-inchi>InChI=1S/C9H10N4S/c1-5-8(14-6(2)12-5)7-3-4-11-9(10)13-7/h3-4H,1-2H3,(H2,10,11,13)</moldb-inchi> <moldb-inchikey>CTFDMGIBHFQWKB-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">206.27</moldb-average-mass> <moldb-mono-mass type="decimal">206.0626173</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM099621</chemdb-id> <dsstox-id>DTXSID70332264</dsstox-id> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00068224</susdat-id> <iupac nil="true"/> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Azoles</klass> <subklass>Thiazoles</subklass> <paper-count type="integer">0</paper-count> <sync-id>CED0094203</sync-id> <structure-inchikey>CTFDMGIBHFQWKB-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>800000000000000002000000000000000000000000000000000000000000000000000002000000040000000000000000000000000000000000200000000000000000000000000004010000000000000000000000000001000000400000000000000000000000040000000000020000800000080000000000040000004000000200000000000001000000000000000000000000000000000000012000000000000080000000000000000084004000000000000000000000000000000000000000000000000000000000000002000000200000000000000000000000001002040000000000000000000000000000000000000040000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAAOAAAADwAAAIABBgBgAAAAAQMGQCgAAAAD BAdAKAAAAAMDBkAoAAAAAwQGAGAAAAABAwZAKAAAAAMEEEAoAAAAAwIGQCgA AAADBAdAKAAAAAMDBkAoAAAAAwQHAGgAAAADAQIHQCgAAAADAwZAaAAAAAMD AQZAaAAAAAMDAQsAAQABAmgMAgNoDAMEAAMFaAwFBmgMBQcgBwhoDAgJaAwJ CiAJC2gMCwxoDAwNaAwGAWgMDQdoDEICAAAABQECAwUGBggJCwwNBxcEAAAA AAAAABY= </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:41:12Z</structure-indexed-at> </compound>