103657 <common-name>Ampalex</common-name> <description>Ampalex is an organic compound with the formula C14H15N3O and an average molecular weight of 241.29 g/mol. Ampalex belongs to the n-acylpiperidines, a subclass of piperidines within the organic compounds. It is further classified as an organoheterocyclic compound. Regarding its biological activity, one protein target has been recorded for this compound: Glutamate receptor 1 (GRIA1).</description> <cas>154235-83-3</cas> <pubchem-id>148184</pubchem-id> <chemical-formula>C14H15N3O</chemical-formula> <weight>241.29</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T10:48:57Z</created-at> <updated-at type="dateTime">2026-08-19T05:44:43Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB06247</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>O=C(N1CCCCC1)C1=CC2=NC=CN=C2C=C1</moldb-smiles> <moldb-formula>C14H15N3O</moldb-formula> <moldb-inchi>InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2</moldb-inchi> <moldb-inchikey>ANDGGVOPIJEHOF-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">241.294</moldb-average-mass> <moldb-mono-mass type="decimal">241.1215121</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>1.45</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM099550</chemdb-id> <dsstox-id>DTXSID70165574</dsstox-id> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00068124</susdat-id> <iupac>6-(piperidine-1-carbonyl)quinoxaline</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Piperidines</klass> <subklass>N-acylpiperidines</subklass> <paper-count type="integer">18</paper-count> <sync-id>CED0030865</sync-id> <structure-inchikey>ANDGGVOPIJEHOF-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>20000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406000000000000000000000000000004000000000000000000000000000002000000020000000000000000000000000000000000000010000000000000000100000000000020102000040000000000000000800000000010000004000000000000000000000000000000000000000000000000000000000000000000000084000000000000004080000008000008000000000000000000000000000000004000001000000004000000000000200000000000000000000000000002040000000000400000000000000000002004000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAASAAAAFAAAAIABCAAoAAAAAwIGACgAAAAD BAcAKAAAAAMDBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGAGAA AAACAgZAKAAAAAMEBkBoAAAAAwMBBkAoAAAAAwQHQCgAAAADAwZAaAAAAAMD AQZAaAAAAAMDAQdAKAAAAAMDBkAoAAAAAwQGQGgAAAADAwEGQGgAAAADAwEL AAEoAgECIAIDAAMEAAQFAAUGAAYHAAEIIAgJaAwJCmgMCgtoDAsMaAwMDWgM DQ5oDA4PaAwPEGgMEBFoDAcCABEIaAwPCmgMQgMAAAAGAwQFBgcCBgkKDxAR CAYLDA0ODwoXBAAAAAAAAAAW </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:41:08Z</structure-indexed-at> </compound>