103620 <common-name>Eltoprazine</common-name> <description>Eltoprazine is an organic compound with the chemical formula C12H16N2O2 and an average molecular weight of 220.27 g/mol. Eltoprazine belongs to the piperazines, a subclass of diazinanes within the organic compounds. It is further categorized under the superclass of organoheterocyclic compounds. Regarding its pharmacological activity, eltoprazine interacts with three recorded protein targets. It acts as an agonist or antagonist of the 5-hydroxytryptamine receptor 1A (HTR1A), the 5-hydroxytryptamine receptor 2C (HTR2C), and the 5-hydroxytryptamine receptor 1B (HTR1B).</description> <cas>98224-03-4</cas> <pubchem-id>65853</pubchem-id> <chemical-formula>C12H16N2O2</chemical-formula> <weight>220.27</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T10:47:12Z</created-at> <updated-at type="dateTime">2026-08-18T18:47:04Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB12883</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C1CN(CCN1)C1=CC=CC2=C1OCCO2</moldb-smiles> <moldb-formula>C12H16N2O2</moldb-formula> <moldb-inchi>InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2</moldb-inchi> <moldb-inchikey>WVLHGCRWEHCIOT-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">220.272</moldb-average-mass> <moldb-mono-mass type="decimal">220.1211778</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>1.06</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM099513</chemdb-id> <dsstox-id>DTXSID5048425</dsstox-id> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00068070</susdat-id> <iupac>1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Diazinanes</klass> <subklass>Piperazines</subklass> <paper-count type="integer">213</paper-count> <sync-id>CED0014977</sync-id> <structure-inchikey>WVLHGCRWEHCIOT-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>1000000000000000000400000000000000000000000010000000040000000000000000000000000000000000000000000000000000080000000000000000000000000000000000008000000000002000000000000000002010002000000000000000000000100020100000080000020000000000000000000000000000000000000000000030008000000000000000008000000000000002000000000c000000008004000000000000000000000000000010000000000000000000000000200000000000000000000000000080040000000400000000000000000000000000008000000</structure-fingerprint> <structure-pattern-fingerprint>4010000009220240000108000108a0000000040000052400003520400204008c48020050028000000000410800800000042000a5408d30010022643000a00010c4110c00020802000090500000620a00005001805000103240000422000241000c280404004082000800940054342009204680100101e0045998200002710002004000084d40000808000200080c0008131d0412440014020000080000408000084300001000c00002000940013ca11002c00000894108401080420008c002100010004404400033018080000401028004000000020050000d000210080001004010000000000000000000024102200000100010804000020008900050400602</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAAQAAAAEgAAAIABBgBgAAAAAgIGAGAAAAAC AgcAKAAAAAMDBgBgAAAAAgIGAGAAAAACAgcAYAAAAAIBBkAoAAAAAwQGQGgA AAADAwEGQGgAAAADAwEGQGgAAAADAwEGQCgAAAADBAZAKAAAAAMECAAoAAAA AwIGAGAAAAACAgYAYAAAAAICCAAoAAAAAwILAAEAAQIAAgMAAwQABAUAAgYg BgdoDAcIaAwICWgMCQpoDAoLaAwLDCAMDQANDgAODwAFAAALBmgMDwogQgMA AAAGAAUEAwIBBgcICQoLBgYMDQ4PCgsXBAAAAAAAAAAW </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:41:07Z</structure-indexed-at> </compound>