74653 <common-name>5,7,8,15-Tetrahydro-4-hydroxy-3-methoxy-6-methyl(1,3)benzodioxolo(5,6-e)(2)benzazecin-14(6H)-one</common-name> <description>5,7,8,15-Tetrahydro-4-hydroxy-3-methoxy-6-methyl(1,3)benzodioxolo(5,6-e)(2)benzazecin-14(6H)-one belongs to the protopine alkaloids, a class of alkaloids and derivatives within the organic compounds. This compound has the formula C20H21N1O5 and an average molecular weight of 355.39 g/mol.</description> <cas>490-52-8</cas> <pubchem-id>1275589</pubchem-id> <chemical-formula>C20H21N1O5</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-04T02:07:24Z</created-at> <updated-at type="dateTime">2026-04-04T02:07:24Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>COC1=C(O)C2=C(CC(=O)C3=CC4=C(OCO4)C=C3CCN(C)C2)C=C1</moldb-smiles> <moldb-formula>C20H21N1O5</moldb-formula> <moldb-inchi>InChI=1S/C20H21NO5/c1-21-6-5-13-8-18-19(26-11-25-18)9-14(13)16(22)7-12-3-4-17(24-2)20(23)15(12)10-21/h3-4,8-9,23H,5-7,10-11H2,1-2H3</moldb-inchi> <moldb-inchikey>RSMSJQDBPYSXHH-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">355.39</moldb-average-mass> <moldb-mono-mass type="decimal">355.141973</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id>1070552</chemspider-id> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM070546</chemdb-id> <dsstox-id>DTXSID90197655</dsstox-id> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00031848</susdat-id> <iupac nil="true"/> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Alkaloids and derivatives</superklass> <klass>Protopine alkaloids</klass> <subklass nil="true"/> <paper-count type="integer">0</paper-count> <sync-id>CED0145638</sync-id> <structure-inchikey>RSMSJQDBPYSXHH-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>10000000000000000200000000000000000000000000210000000020400000000000000020000000008040000000000000000000400000000000000000000000000000000000000000000000000020800000000100000000002001000000020000010000000040000000100000000000820100000000000000080000000000080040200000000000000008004000000000000000000200080000000000000000000000000004000000080200000000000000000000008000000000000080000408000000002000000000010000000000000000000000200200000000000080000000000000030040008000400000000020000020080000000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ������������������������€���`�������(������@(������@(�������h�������@(������@(�������`�������(�������(������@(������@h�������@(������@(�������(�������`�������(������@h�������@(�������`�������`������� ������`�������`������@h�������@h������������ ��h��� ��h���h�������� (�� �h���h�� h� � ������ �h���h������������������h���h���h����� h��� B����������� �� ���������� �� �� �������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:23:05Z</structure-indexed-at> </compound>