20607 <common-name>SR144190</common-name> <description>SR144190 belongs to the morpholines, a subclass of oxazinanes within the organic compounds. It is an organoheterocyclic compound with the formula C33H39ClF2N4O3. With an average molecular weight of 613.15 g/mol, SR144190 is a heavy molecule.</description> <cas>181640-09-5</cas> <pubchem-id>9916195</pubchem-id> <chemical-formula>C33H39ClF2N4O3</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2016-05-22T06:11:48Z</created-at> <updated-at type="dateTime">2026-04-03T01:25:19Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>Cl.CN(C)C(O)=NC1(CCN(CC[C@]2(CN(CCO2)C(=O)C2=CC=CC=C2)C2=CC(F)=C(F)C=C2)CC1)C1=CC=CC=C1</moldb-smiles> <moldb-formula>C33H39ClF2N4O3</moldb-formula> <moldb-inchi>InChI=1S/C33H38F2N4O3.ClH/c1-37(2)31(41)36-32(26-11-7-4-8-12-26)15-18-38(19-16-32)20-17-33(27-13-14-28(34)29(35)23-27)24-39(21-22-42-33)30(40)25-9-5-3-6-10-25;/h3-14,23H,15-22,24H2,1-2H3,(H,36,41);1H/t33-;/m0./s1</moldb-inchi> <moldb-inchikey>CUYCXSCEWNTJEZ-WAQYZQTGSA-N</moldb-inchikey> <moldb-average-mass type="decimal">613.15</moldb-average-mass> <moldb-mono-mass type="decimal">612.2678752</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id>8091843</chemspider-id> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM019502</chemdb-id> <dsstox-id>DTXSID4047339</dsstox-id> <toxcast-id>47339</toxcast-id> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00015694</susdat-id> <iupac nil="true"/> <moldb-polar-surface-area>68.61</moldb-polar-surface-area> <moldb-refractivity>160.21159999999992</moldb-refractivity> <moldb-polarizability>61.535452331763196</moldb-polarizability> <moldb-rotatable-bond-count>7</moldb-rotatable-bond-count> <moldb-acceptor-count>6</moldb-acceptor-count> <moldb-donor-count>1</moldb-donor-count> <moldb-pka-strongest-acidic>-2.382933343020169</moldb-pka-strongest-acidic> <moldb-pka-strongest-basic>15.000001161214401</moldb-pka-strongest-basic> <moldb-physiological-charge>1</moldb-physiological-charge> <moldb-number-of-rings>5</moldb-number-of-rings> <moldb-alogps-logp>4.50</moldb-alogps-logp> <moldb-alogps-logs>-5.29</moldb-alogps-logs> <moldb-alogps-solubility>2.94e-03 g/l</moldb-alogps-solubility> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Oxazinanes</klass> <subklass>Morpholines</subklass> <paper-count type="integer">4</paper-count> <sync-id>CED0044614</sync-id> <structure-inchikey>CUYCXSCEWNTJEZ-WAQYZQTGSA-N</structure-inchikey> 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