18925 <common-name>Tolnaftate</common-name> <description nil="true"/> <cas>2398-96-1</cas> <pubchem-id>39211</pubchem-id> <chemical-formula>C19H17NOS</chemical-formula> <weight>307.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2016-05-22T04:40:34Z</created-at> <updated-at type="dateTime">2026-05-14T16:41:12Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB00525</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CN(C(=S)OC1=CC2=CC=CC=C2C=C1)C1=CC=CC(C)=C1</moldb-smiles> <moldb-formula>C19H17NOS</moldb-formula> <moldb-inchi>InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3</moldb-inchi> <moldb-inchikey>FUSNMLFNXJSCDI-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">307.409</moldb-average-mass> <moldb-mono-mass type="decimal">307.103084861</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>5.75</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id>5309</chemspider-id> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM017820</chemdb-id> <dsstox-id>DTXSID3042477</dsstox-id> <toxcast-id>42477</toxcast-id> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00000538</susdat-id> <iupac>N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide</iupac> <moldb-polar-surface-area>12.47</moldb-polar-surface-area> <moldb-refractivity>94.92040000000004</moldb-refractivity> <moldb-polarizability>34.22480823447255</moldb-polarizability> <moldb-rotatable-bond-count>3</moldb-rotatable-bond-count> <moldb-acceptor-count>1</moldb-acceptor-count> <moldb-donor-count>0</moldb-donor-count> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic>0.07504048749554171</moldb-pka-strongest-basic> <moldb-physiological-charge>0</moldb-physiological-charge> <moldb-number-of-rings>3</moldb-number-of-rings> <moldb-alogps-logp>4.87</moldb-alogps-logp> <moldb-alogps-logs>-5.75</moldb-alogps-logs> <moldb-alogps-solubility>5.46e-04 g/l</moldb-alogps-solubility> </compound>