4983 Linoleic acid Linoleic acid is a doubly unsaturated fatty acid, also known as an omega-6 fatty acid, occurring widely in plant glycosides. In this particular polyunsaturated fatty acid (PUFA), the first double bond is located between the sixth and seventh carbon atom from the methyl end of the fatty acid (n-6). Linoleic acid is an essential fatty acid in human nutrition because it cannot be synthesized by humans. It is used in the biosynthesis of prostaglandins (via arachidonic acid) and cell membranes. (From Stedman, 26th ed). 60-33-3 5280450 C18H32O2 280.4 -8.5 °C 230°C No indication of carcinogenicity to humans (not listed by IARC). 2014-09-11T05:22:52Z 2026-04-17T17:54:53Z http://en.wikipedia.org/wiki/Linoleic acid C01595 17351 D019787 DB14104 EIC true CCCCC\C=C/C\C=C/CCCCCCCC(O)=O C18H32O2 InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9- OYHQOLUKZRVURQ-HZJYTTRNSA-N 280.4455 280.240230268 Endogenous Liquid 7.05 HMDB00673 4444105 Walborsky, Harry M.; Davis, Robert H.; Howton, David R. A total synthesis of linoleic acid. Journal of the American Chemical Society (1951), 73 2590-4. CHEM003884 DTXSID2025505 NS00010521 (9Z,12Z)-octadeca-9,12-dienoic acid