<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">4976</id>
  <title>T3D4921</title>
  <common-name>Diflubenzuron</common-name>
  <description>Insecticide, interfering with chitin deposition by oral absorption. Diflubenzuron is used on soya beans, citrus, tea, vegetables and mushrooms. Also used as an insecticide in feed for poultry and pigs and as a controlled release bolus in cattle



Diflubenzuron belongs to the family of N-Phenylureas. These are compounds containing a N-phenylurea moiety, which is structurally characterized by a phenyl group linked to one nitrogen atom of an urea group.</description>
  <cas>35367-38-5</cas>
  <pubchem-id>37123</pubchem-id>
  <chemical-formula>C14H9ClF2N2O2</chemical-formula>
  <weight nil="true"/>
  <appearance>White powder.</appearance>
  <melting-point>230 - 232 °C</melting-point>
  <boiling-point></boiling-point>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure></route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>One of the metabolites of diflubenzuron, PCA, is a proximate carcinogen. It is conjugated to form the carcinogen that can ionize and reat with DNA to form adducts which result in splenic tumor formation.</mechanism-of-toxicity>
  <metabolism></metabolism>
  <toxicity></toxicity>
  <lethaldose></lethaldose>
  <carcinogenicity>para-Chloroaniline is possibly carcinogenic to humans (Group 2B). (L135)</carcinogenicity>
  <use-source></use-source>
  <min-risk-level></min-risk-level>
  <health-effects>One of the metabolites of diflubenzuron, PCA, has severe health effects. It is associated with cancer of the spleen and liver and osteosarcomas in male rats. Another metabolite of diflubenzuron also has carcinogenic potential and the same carcinogenic potency as PCA. </health-effects>
  <symptoms></symptoms>
  <treatment></treatment>
  <created-at type="dateTime">2014-09-11T05:22:35Z</created-at>
  <updated-at type="dateTime">2026-03-31T17:48:27Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia></wikipedia>
  <uniprot-id></uniprot-id>
  <kegg-compound-id>C14427</kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id>34703</chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id></ctd-id>
  <stitch-id></stitch-id>
  <drugbank-id></drugbank-id>
  <pdb-id></pdb-id>
  <actor-id></actor-id>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC=C(Cl)C=C1</moldb-smiles>
  <moldb-formula>C14H9ClF2N2O2</moldb-formula>
  <moldb-inchi>InChI=1S/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)</moldb-inchi>
  <moldb-inchikey>QQQYTWIFVNKMRW-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">310.683</moldb-average-mass>
  <moldb-mono-mass type="decimal">310.032061659</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp>3.88</logp>
  <hmdb-id>HMDB31778</hmdb-id>
  <chembl-id></chembl-id>
  <chemspider-id>34065</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM003877</chemdb-id>
  <dsstox-id>DTXSID1024049</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00009540</susdat-id>
  <iupac>3-(4-chlorophenyl)-1-(2,6-difluorobenzoyl)urea</iupac>
</compound>
