4699 Acrivastine Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine (like its base molecule triprolidine) and works by blocking Histamine H1 receptors. Anticholinergic (primarily antimuscarinic) effects develop in overdose due to antagonism of central H1 receptors. Large overdoses of H1 blockers, particularly diphenhydramine, may cause sodium channel antagonism. Decongestants can lead to sympathomimetic (e.g., hypertension, tachycardia, hyperventilation, intercranial hemorrhage) symptoms. (L2048) 87848-99-5 5284514 C22H24N2O2 White powder. No indication of carcinogenicity to humans (not listed by IARC). Acrivastine is a medication used for the treatment of allergies and hay fever. 2014-09-08T02:39:57Z 2026-05-14T19:06:13Z DB09488 true [H]\C(CN1CCCC1)=C(\C1=CC=C(C)C=C1)C1=CC=CC(=N1)C(\[H])=C(/[H])C(O)=O C22H24N2O2 InChI=1S/C22H24N2O2/c1-17-7-9-18(10-8-17)20(13-16-24-14-2-3-15-24)21-6-4-5-19(23-21)11-12-22(25)26/h4-13H,2-3,14-16H2,1H3,(H,25,26)/b12-11+,20-13+ PWACSDKDOHSSQD-IUTFFREVSA-N 348.4382 348.183778022 Exogenous Solid 1.71 CHEMBL1224 4447574 CHEM003603 DTXSID6022555 NS00003303 (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid 53.43000000000001 115.08009999999997 39.09482423992762 6 4 1 3.68137138223122 8.629973178875698 0 3 4.29 -4.54 9.94e-03 g/l