<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">4559</id>
  <title>T3D4505</title>
  <common-name>Fenarimol</common-name>
  <description>Fenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, blackspot and mildew fungi. It is used on ornamental plants, trees, lawns, tomatoes, peppers, eggplants, cucumbers and melons. It is mainly used to control powdery mildew. It works by inhibiting the fungus's biosynthesis of important steroid molecules.</description>
  <cas>60168-88-9</cas>
  <pubchem-id>43226</pubchem-id>
  <chemical-formula>C17H12Cl2N2O</chemical-formula>
  <weight nil="true"/>
  <appearance>White powder.</appearance>
  <melting-point>117 - 119 °C</melting-point>
  <boiling-point></boiling-point>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure></route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Fenarimol is an antiandrogen. It has effects on the reproductive organs and prostate gene expression levels. Studies suggested that the adverse effects of Fenarimol in males are mediated at least partialy via antagonism or androgen receptor.</mechanism-of-toxicity>
  <metabolism></metabolism>
  <toxicity></toxicity>
  <lethaldose></lethaldose>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source></use-source>
  <min-risk-level></min-risk-level>
  <health-effects></health-effects>
  <symptoms></symptoms>
  <treatment></treatment>
  <created-at type="dateTime">2014-08-29T06:51:43Z</created-at>
  <updated-at type="dateTime">2026-03-25T19:26:23Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>http://en.wikipedia.org/wiki/Fenarimol</wikipedia>
  <uniprot-id></uniprot-id>
  <kegg-compound-id>C11226</kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id></ctd-id>
  <stitch-id></stitch-id>
  <drugbank-id></drugbank-id>
  <pdb-id></pdb-id>
  <actor-id></actor-id>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>OC(C1=CC=C(Cl)C=C1)(C1=CN=CN=C1)C1=CC=CC=C1Cl</moldb-smiles>
  <moldb-formula>C17H12Cl2N2O</moldb-formula>
  <moldb-inchi>InChI=1S/C17H12Cl2N2O/c18-14-7-5-12(6-8-14)17(22,13-9-20-11-21-10-13)15-3-1-2-4-16(15)19/h1-11,22H</moldb-inchi>
  <moldb-inchikey>NHOWDZOIZKMVAI-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">331.196</moldb-average-mass>
  <moldb-mono-mass type="decimal">330.03266843</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp></logp>
  <hmdb-id>HMDB40599</hmdb-id>
  <chembl-id>CHEMBL28971</chembl-id>
  <chemspider-id>39394</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM003465</chemdb-id>
  <dsstox-id>DTXSID2032390</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00000135</susdat-id>
  <iupac nil="true"/>
  <moldb-polar-surface-area>46.010000000000005</moldb-polar-surface-area>
  <moldb-refractivity>89.58539999999999</moldb-refractivity>
  <moldb-polarizability>32.33446898551444</moldb-polarizability>
  <moldb-rotatable-bond-count>3</moldb-rotatable-bond-count>
  <moldb-acceptor-count>3</moldb-acceptor-count>
  <moldb-donor-count>1</moldb-donor-count>
  <moldb-pka-strongest-acidic>12.12652991772322</moldb-pka-strongest-acidic>
  <moldb-pka-strongest-basic>1.04306768494885</moldb-pka-strongest-basic>
  <moldb-physiological-charge>0</moldb-physiological-charge>
  <moldb-number-of-rings>3</moldb-number-of-rings>
  <moldb-alogps-logp>3.13</moldb-alogps-logp>
  <moldb-alogps-logs>-4.72</moldb-alogps-logs>
  <moldb-alogps-solubility>6.27e-03 g/l</moldb-alogps-solubility>
</compound>
