4503 T3D4449 Guanosine Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a beta-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate). . The nucleoside guanosine exert important neuroprotective and neuromodulator roles in the central nervous system, which may be related to inhibition of the glutamatergic neurotransmission activity. Guanosine is the specific extracellular guanine-based purines effector and indicate that its conversion occurs not only in the central nervous system but also peripherally. (A3508). 118-00-3 6802 C10H13N5O5 White powder. 239°C 0.7 mg/mL at 18°C No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-08-29T06:51:22Z 2026-04-13T21:59:51Z Guanosine C00387 16750 GUANOSINE DB02857 GMP true NC1=NC2=C(N=CN2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1 C10H13N5O5 InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1 NYHBQMYGNKIUIF-UUOKFMHZSA-N 283.2407 283.091668551 Endogenous Solid -1.9 HMDB00133 CHEMBL375655 6544 <p>Hitoshi Enei, Katsuaki Sato, Yoshio Hirose, &#8220;Method of producing guanosine by fermentation.&#8221; U.S. Patent US3960660, issued April, 1971.</p> CHEM003409 DTXSID00893055 NS00009027 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one