4485
T3D4431
Deoxyuridine
2'-Deoxyuridine is a naturally occurring nucleoside. It is similar in chemical structure to uridine, but without the 2'-hydroxyl group. It is considered to be an antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemia due to vitamin B12 and folate deficiencies.
951-78-0
13712
C9H12N2O5
White powder.
167°C
No indication of carcinogenicity to humans (not listed by IARC).
This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.
2014-08-29T06:51:15Z
2026-05-14T17:32:33Z
Deoxyuridine
C00526
16450
DEOXYURIDINE
DB02256
DUR
true
OC[C@H]1O[C@H](C[C@@H]1O)N1C=CC(=O)NC1=O
C9H12N2O5
InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1
MXHRCPNRJAMMIM-SHYZEUOFSA-N
228.202
228.074621504
Endogenous
Solid
-1.51
HMDB00012
CHEMBL353955
13118
<p>Kenzo Watanabe, Yoshinori Kato, Masahiko Saito, Takeo Oba, Hisashi Fukushima, Takeshi Hara, “5-fluoro-2’-deoxyuridine derivatives and a process for the preparation thereof.” U.S. Patent US4605645, issued May, 1984.</p>
CHEM003391
DTXSID30883621
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
99.1
51.05490000000001
21.061427774885466
2
5
3
9.705729612726527
-2.9780835884997945
0
2
-1.49
-0.40
9.06e+01 g/l