4462 Mevalonic acid Mevalonic acid is a key organic compound in biochemistry. It is a precursor in the biosynthetic pathway, known as the HMG-CoA reductase pathway, that produces terpenes and steroids. Mevalonate is produced by NADPH from 3-hydroxy-3-methylglutaryl CoA via reduction. This reaction occurs in the cytosol. It is the committed step in cholesterol synthesis. 150-97-0 449 C6H12O4 White powder. 24 - 27°C No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-08-29T06:51:04Z 2026-04-13T22:21:58Z Mevalonic acid C00418 25351 MEVALONATE DB03518 true CC(O)(CCO)CC(O)=O C6H12O4 InChI=1S/C6H12O4/c1-6(10,2-3-7)4-5(8)9/h7,10H,2-4H2,1H3,(H,8,9) KJTLQQUUPVSXIM-UHFFFAOYSA-N 148.1571 148.073558872 Endogenous Solid HMDB00227 436 CHEM003368 DTXSID5040546 NS00015151 3,5-dihydroxy-3-methylpentanoic acid