4431 Histamine Histamine is an amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. 51-45-6 774 C5H9N3 White powder. 86°C 209.5°C (409.1°F) No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-08-29T06:37:04Z 2026-04-14T15:38:30Z Histamine C00388 18295 HISTAMINE DB05381 HSM true NCCC1=CNC=N1 C5H9N3 InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) NTYJJOPFIAHURM-UHFFFAOYSA-N 111.1451 111.079647303 Endogenous Solid -0.7 HMDB00870 CHEMBL90 753 Pyman, Frank L. 2-Thiol-4(5)-b-aminoethylglyoxaline (2-thiolhistamine). Journal of the Chemical Society (1930), 98-100. CHEM003337 DTXSID4023125 REACH SI00007243 NS00004684 2-(1H-imidazol-4-yl)ethan-1-amine