4426 Hawkinsin Hawkinsin is a sulfur amino acid identified as (2-l-cystein-S-yl, 4-dihydroxycyclohex-5-en-1-yl)acetic acid. Patients with hawkinsinuria excrete this metabolite in their urine throughout their life, although symptoms of metabolic acidosis and tyrosinemia improve in the first year of life. Alterations in the structure and activity of 4-hydroxyphenylpyruvic acid dioxygenase are causally related to two different metabolic disorders, tyrosinemia type III and hawkinsinuria. (A3451). 63224-90-8 173909 C11H17NO6S White powder. No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. Chronically high levels of hawkinsin are associated with Hawkinsinuria. 2014-08-29T06:36:15Z 2026-04-06T13:07:43Z true NC(CSC1CC(O)C=CC1(O)CC(O)=O)C(O)=O C11H17NO6S InChI=1S/C11H17NO6S/c12-7(10(16)17)5-19-8-3-6(13)1-2-11(8,18)4-9(14)15/h1-2,6-8,13,18H,3-5,12H2,(H,14,15)(H,16,17) SPXVLTDISXZSFM-UHFFFAOYSA-N 291.321 291.077657971 Endogenous Solid HMDB02354 151775 CHEM003332 NS00125392 141.08 68.53380000000001 27.82939123320438 6 7 5 1.93942479227327 9.13420766816257 -1 1 -3.19 -1.41 1.14e+01 g/l