4411 3-Hydroxyglutaric acid 3-Hydroxyglutaric acid is a key metabolite in glutaryl co-enzyme A dehydrogenase deficiency, and is considered to be a potential neurotoxin. The urine level of 3-Hydroxyglutaric acid is elevated in Glutaric Aciduria Type I (glutaryl-CoA dehydrogenase deficiency) patients. (A3440). 638-18-6 181976 C5H8O5 White powder. No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. Chronically high levels of 3-hydroxyglutaric acid are associated with Glutaric Aciduria Type I. 2014-08-29T06:33:48Z 2026-04-05T11:33:09Z R-2-HYDROXYGLUTARATE DB04594 3HG true OC(CC(O)=O)CC(O)=O C5H8O5 InChI=1S/C5H8O5/c6-3(1-4(7)8)2-5(9)10/h3,6H,1-2H2,(H,7,8)(H,9,10) ZQHYXNSQOIDNTL-UHFFFAOYSA-N 148.114 148.037173366 Endogenous Solid HMDB00428 CHEMBL556937 158277 CHEM003317 DTXSID00213239 3-hydroxypentanedioic acid