4400
T3D4346
Beta-Alanine
Beta-alanine is the only naturally occurring beta-amino acid - the amino group is at the β-position from the carboxylate group. It is formed in vivo by the degradation of dihydrouracil and carnosine. It is a component of the naturally occurring peptides carnosine and anserine and also of pantothenic acid (Vitamin B-5) which itself is a component of coenzyme A. Under normal conditions, beta-alanine is metabolized into acetic acid. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing gamma-aminobutyric acid. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
107-95-9
239
C3H7NO2
89.09
White powder.
200°C
545.0 mg/mL
No indication of carcinogenicity to humans (not listed by IARC).
This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.
Chronically high levels of beta-alanine are associated with at least 2 inborn errors of metabolism including: GABA-Transaminase Deficiency and Methylmalonate Semialdehyde Dehydrogenase Deficiency.
2014-08-29T06:30:45Z
2026-05-14T17:48:07Z
beta-Alanine
C00099
16958
B-ALANINE
DB03107
BAL
true
NCCC(O)=O
C3H7NO2
InChI=1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)
UCMIRNVEIXFBKS-UHFFFAOYSA-N
89.0932
89.047678473
Endogenous
Solid
-3.05
HMDB00056
CHEMBL297569
234
<p>Erwin Grill, Ernst-Ludwig Winnacker, Meinhart H. Zenk, “Cysteine-rich peptides having gamma-glutamic acid and beta-alanine units, a process for their preparation and their use.” U.S. Patent US4883861, issued March, 1978.</p>
CHEM003306
DTXSID0030823
NS00009116
3-aminopropanoic acid
63.32
20.7028
8.617827871827803
2
3
2
4.084398800362644
10.307201201262663
0
0
-3.26
0.74
4.94e+02 g/l