4362 T3D4308 Indole Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a degradation product of the amino acid tryptophan. It occurs naturally in human feces and has an intense fecal smell. At very low concentrations, however, it has a flowery smell, and is a constituent of many flower scents (such as orange blossoms) and perfumes. Natural jasmine oil, used in the perfume industry, contains around 2.5% of indole. Indole also occurs in coal tar. The participation of the nitrogen lone electron pair in the aromatic ring means that indole is not a base, and it does not behave like a simple amine. 120-72-9 798 C8H7N 117.15 White powder. 52.5°C 253°C (487.4°F) 3.56 mg/mL No indication of carcinogenicity to humans (not listed by IARC). This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation. 2014-08-29T06:17:59Z 2026-05-14T18:08:53Z Indole C00463 16881 INDOLE DB04532 IND true N1C=CC2=C1C=CC=C2 C8H7N InChI=1S/C8H7N/c1-2-4-8-7(3-1)5-6-9-8/h1-6,9H SIKJAQJRHWYJAI-UHFFFAOYSA-N 117.1479 117.057849229 Endogenous Solid 2.14 HMDB00738 CHEMBL15844 776 <p>Ernst Schefczik, &#8220;Preparation of indole derivatives.&#8221; U.S. Patent US4611064, issued June, 1900.</p> CHEM003268 DTXSID0020737 NS00010849 1H-indole 15.79 37.1445 12.81574628396194 0 0 1 16.437037050201045 0 2 2.29 -1.34 5.31e+00 g/l