4347
T3D4293
Uracil
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions. UDP and UTP regulate CPSase II activity in animals. UDP-glucose regulates the conversion of glucose to galactose in the liver and other tissues in the process of carbohydrate metabolism. Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes.
66-22-8
1174
C4H4N2O2
White powder.
330°C
3.6 mg/mL
No indication of carcinogenicity to humans (not listed by IARC).
This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.
2014-08-29T06:16:24Z
2026-05-14T17:49:55Z
Uracil
C00106
17568
URACIL
DB03419
URA
true
O=C1NC=CC(=O)N1
C4H4N2O2
InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
ISAKRJDGNUQOIC-UHFFFAOYSA-N
112.0868
112.027277382
Endogenous
Solid
-1.07
HMDB00300
CHEMBL566
1141
<p>Kurt Klemm, Wolfgang Schoetensack, Wolfgang Prusse, “Aryl-substituted piperazinyl-alkylamino-uracils, -uracil ethers and -uracil thioethers and method for their production.” U.S. Patent US3957786, issued September, 1951.</p>
CHEM003253
DTXSID4021424
NS00002070
1,2,3,4-tetrahydropyrimidine-2,4-dione
58.2
25.9693
9.36551055096874
0
2
2
8.803392786213806
-5.5116186106121114
0
1
-1.20
-0.63
2.65e+01 g/l