4334 Succinyladenosine Succinyladenosine (SAdo) is one of the dephosphorylated enzyme substrate that accumulates in body fluids of patients with adenylosuccinate lyase (ADSL) deficiency, the other being 5-amino-4-imidazole-N-succinocarboxamide riboside (SAICAr). ADSL is an inherited metabolic disease characterized by various degrees of psychomotor retardation. The severity of the clinical presentation correlates with a low S-Ado/SAICAr ratio in body fluids. Normally Succinyladenosine is not found in blood or CSF but may be detected in trace amounts in urine. (OMIM 103050). (A3374, A3375). 4542-23-8 20849086 C14H17N5O8 White powder. 233 - 238°C No indication of carcinogenicity to humans (not listed by IARC). 2014-08-29T06:13:18Z 2026-04-06T13:22:15Z 71169 true OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N[C@@H](CC(O)=O)C(O)=O)N=CN=C12 C14H17N5O8 InChI=1S/C14H17N5O8/c20-2-6-9(23)10(24)13(27-6)19-4-17-8-11(15-3-16-12(8)19)18-5(14(25)26)1-7(21)22/h3-6,9-10,13,20,23-24H,1-2H2,(H,21,22)(H,25,26)(H,15,16,18)/t5-,6+,9+,10+,13+/m0/s1 VKGZCEJTCKHMRL-VWJPMABRSA-N 383.3135 383.107712545 Endogenous Solid HMDB00912 17216022 Buck, Ildiko; Reese, Colin B. An unambiguous synthesis of adenylosuccinic acid and its constituent nucleoside. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1990), (11), 2937-42. CHEM003240 NS00126007 200.14999999999998 85.30290000000001 34.83173121059809 7 12 6 3.1388685314254663 4.584629192365606 -2 3 -1.32 -1.70 7.62e+00 g/l