4303 Oxoglutaric acid Alpha-ketoglutaric acid is an important biological compound and is a key intermediate in the Krebs cycle. Alpha-ketoglutaric acid occurs naturally within cells. One of its functions is to combine with ammonia to form glutamic acid and then glutamine. Another function is to combine with nitrogen released in the cell, therefore preventing nitrogen overload. . 328-50-7 51 C5H6O5 White powder. 115.5°C 541.5 mg/mL No indication of carcinogenicity to humans (not listed by IARC). 2014-08-29T06:03:30Z 2026-04-14T17:32:46Z Oxoglutarate C00026 30915 2-KETOGLUTARATE DB08845 AKG true OC(=O)CCC(=O)C(O)=O C5H6O5 InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10) KPGXRSRHYNQIFN-UHFFFAOYSA-N 146.0981 146.021523302 Endogenous Solid HMDB00208 CHEMBL1686 50 Tanaka, Katsunobu; kimura, Kazu; Yamaguchi, Ken. Fermentative production of a-oxoglutaric acid. U.S. (1973), 4 pp. CHEM003209 DTXSID5033179 2-oxopentanedioic acid