4138 Veratramine Veratramine is a hypotensive alkaloid isolated from the rhizomes of Veratrum. 60-70-8 6070 C27H39NO2 White powder. Veratramine produces a characteristic excitatory action on the central nervous system, producing both tremor and a characteristic "struggling" behavior. This behavioral excitation is accompanied by changes in serotonin content in hypothalamus. The central serotonin agonist methysergide in doses of 5--15 mg per kg produces a dose-dependent inhibition of veratramine's action, while parachlorophenylalanine has no effect. (A15440) No indication of carcinogenicity to humans (not listed by IARC). Veratramine is a hypotensive alkaloid isolated from the rhizomes of Veratrum. 2014-08-29T05:04:53Z 2026-04-03T04:51:24Z C10829 CHEBI:9951 true [H][C@](C)(C1=C(C)C2=C(C=C1)[C@]1([H])CC=C3C[C@@]([H])(O)CC[C@]3(C)[C@@]1([H])C2)[C@]1([H])NC[C@@]([H])(C)C[C@@]1([H])O C27H39NO2 InChI=1S/C27H39NO2/c1-15-11-25(30)26(28-14-15)17(3)20-7-8-21-22-6-5-18-12-19(29)9-10-27(18,4)24(22)13-23(21)16(20)2/h5,7-8,15,17,19,22,24-26,28-30H,6,9-14H2,1-4H3/t15-,17-,19-,22-,24-,25+,26-,27-/m0/s1 MALFODICFSIXPO-KFKQDBFTSA-N 409.6041 409.298079497 Exogenous Solid CHEMBL464724 5845 CHEM003044 NS00018021 52.489999999999995 124.08889999999998 49.65718001457323 2 3 3 14.57388006587033 9.913187751691336 1 5 4.57 -5.71 7.95e-04 g/l