4135 Matrine Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and μ-receptor agonist. 519-02-8 91466 C15H24N2O White powder. The nervous system is the main target organ by the toxicity of matrine. Morphological observation revealed degenerative changes of the nerve cells in the brain tissue of the mice. (A15436) Matrine has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and µ-receptor agonist. Matrine possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities. (Wikipedia) No indication of carcinogenicity to humans (not listed by IARC). Matrine is an alkaloid found in plants from the Sophora genus. 2014-08-29T05:04:05Z 2026-04-05T10:23:56Z C10774 true [H][C@]12CCCN3CCC[C@]([H])([C@@]4([H])CCCC(=O)N4C1)[C@]23[H] C15H24N2O InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-/m0/s1 ZSBXGIUJOOQZMP-JLNYLFASSA-N 248.3639 248.1888634 Exogenous Solid CHEMBL204860 82591 CHEM003041 DTXSID00274188 NS00066991 23.55 71.4485 28.688682598674603 0 2 0 9.75220211509645 1 4 1.92 -1.60 6.24e+00 g/l