3997 Vinclozolin Vinclozolin (trade names: Ronilan, Curalan, Vorlan, Touche) is a common dicarboximide fungicide used to control diseases, such as blights, rots and molds in vineyards, and on fruits and vegetables such as raspberries, lettuce, kiwi, snap beans, and onions. It is also used on turf on golf courses. Two common fungi that vinclozolin is used to protect crops against are botrytis cinerea and sclerotinia scleotiorun. First registered in 1981, vinclozolin is widely used but its overall application has declined. As a pesticide, vinclozolin is regulated by the United States Environmental Protection Agency (U.S. EPA). It has gone through a series of tests and regulations in order to evaluate the risks and hazards to the environment and animals. Among the research, a main finding is that vinclozolin has been shown to be an endocrine disruptor with antiandrogenic effects. 50471-44-8 39676 C12H9Cl2NO3 White powder. Vinclozolin and some of its metabolites have antiandrogenic activity. Vinclozolin's main toxic effects are related to its antiandrogenic activity. They compete with androgens for the androgen receptor, inhibit androgen receptor-DNA binding, and alter androgen-dependent gene expression. No indication of carcinogenicity to humans (not listed by IARC). This is a man-made compound that is used as a pesticide. 2013-04-25T07:56:55Z 2026-03-26T18:34:55Z C10981 true CC1(OC(=O)N(C1=O)C1=CC(Cl)=CC(Cl)=C1)C=C C12H9Cl2NO3 InChI=1S/C12H9Cl2NO3/c1-3-12(2)10(16)15(11(17)18-12)9-5-7(13)4-8(14)6-9/h3-6H,1H2,2H3 FSCWZHGZWWDELK-UHFFFAOYSA-N 286.111 284.995948573 Exogenous Solid CHEMBL513221 36278 CHEM002903 DTXSID4022361 NS00000531 46.61 67.00150000000001 26.193033458615048 2 3 0 -5.282967397384969 0 2 3.14 -3.90 3.57e-02 g/l