3989 Thiophanate-methyl Thiophanate-Methyl (TM) is a systemic fungicide. It was first registered to be used as a fungicide by the EPA in 1973. It is effective against a wide range of fungal pathogens including: eyespot and other diseases of cereals; scab on apples and pears; Monilia disease and Gloeosporim rot on apples; Monilia app. On stone fruit; Canker on fruit trees; powdery mildews on pome fruit, stone fruit, vegetables, cucurbits, strawberries, vines, roses. Thiophanate methyl is also used on almonds, pecans, tea, coffee, peanuts, soya beans, tobacco, chestnuts, sugar cane, citrus fruit, figs, hops, mulberries, and many other crops. 23564-05-8 3032791 C12H14N4O4S2 White powder. Not listed by IARC. This is a man-made compound that is used as a pesticide. Thiophanate-methyl is likely a human carcinogen. It increases of risk of liver tumours in mice. Thyroid/parathyroid weights were increased The developmental toxicity studies showed the decreased fetal body weight and increases in skeletal variations in the fetuses of rabbits exposed to thiophanate-methyl. It induced histopathological damages in rat thyroid and adrenal glands. Thiophanate-methyl can cause skin, eye and respiratory irritation, shortness of breath, chest pains, burning eyes, dizziness, and fatigue. Rinse dermal exposure with water, irrigate exposed eyes with water, remove the contaminated clothing. Intubate the patients with altered mental status or airway injury. Treat acidosis and seizures. Patients should be treated with activated charcoal after large ingestions of thiophanate-methyl if they can drink the charcoal. 2013-04-25T07:56:55Z 2026-03-26T22:56:33Z C14432 35014 true COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC C12H14N4O4S2 InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22) QGHREAKMXXNCOA-UHFFFAOYSA-N 342.394 342.045646336 Exogenous Solid CHEMBL487187 2297683 CHEM002895 DTXSID1024338 NS00004932 100.72000000000001 91.4982 33.09733132953634 4 2 4 7.795292627964617 0 1 1.57 -4.77 5.83e-03 g/l