<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">3803</id>
  <title>T3D3749</title>
  <common-name>Asteltoxin</common-name>
  <description>Asteltoxin is a mycotoxin of Aspergillus stellatus and Emericella varicolorAsteltoxin belongs to the family of Furofurans. These are organic compounds containing a two furan rings fused to each other.</description>
  <cas>79663-49-3</cas>
  <pubchem-id>6438150</pubchem-id>
  <chemical-formula>C23H30O7</chemical-formula>
  <weight nil="true"/>
  <appearance>White powder.</appearance>
  <melting-point>130 - 132°C</melting-point>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility nil="true"/>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Oral, dermal, inhalation, and parenteral (contaminated drugs). (A3101)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Asteltoxin inhibits mitochondrial respiration by affecting its energy transfer system. It does this by inhibiting Mg2+ and Na+/K+-ATPases. (A3002, A3003, A3031)</mechanism-of-toxicity>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose>LD50: 5.9 mg/kg (Intraperitoneal, Mouse) (A3031)</lethaldose>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Asteltoxin is a mycotoxin produced by the fungi Aspergillus stellatus and Emericella variecolor. It can be found in contaminated corn crops. (A3031)</use-source>
  <min-risk-level nil="true"/>
  <health-effects>Asteltoxin affects the central nervous system. (A3031)</health-effects>
  <symptoms>Asteltoxin can cause respiratory arrest and paralysis. (A3031)</symptoms>
  <treatment nil="true"/>
  <created-at type="dateTime">2010-05-12T16:57:23Z</created-at>
  <updated-at type="dateTime">2026-04-06T11:17:57Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia nil="true"/>
  <uniprot-id nil="true"/>
  <kegg-compound-id nil="true"/>
  <omim-id nil="true"/>
  <chebi-id nil="true"/>
  <biocyc-id nil="true"/>
  <ctd-id nil="true"/>
  <stitch-id nil="true"/>
  <drugbank-id nil="true"/>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>[H]/C(=C(/[H])\C(\[H])=C(/[H])C1=C(C)C(OC)=CC(=O)O1)/C(/[H])=C(\[H])C1OC2OC(CC)C(C)(O)C2(C)C1O</moldb-smiles>
  <moldb-formula>C23H30O7</moldb-formula>
  <moldb-inchi>InChI=1S/C23H30O7/c1-6-18-23(4,26)22(3)20(25)16(29-21(22)30-18)12-10-8-7-9-11-15-14(2)17(27-5)13-19(24)28-15/h7-13,16,18,20-21,25-26H,6H2,1-5H3/b8-7+,11-9+,12-10+</moldb-inchi>
  <moldb-inchikey>GPXPJKFETRLRAS-BGSVYHRFSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">418.4801</moldb-average-mass>
  <moldb-mono-mass type="decimal">418.199153314</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp nil="true"/>
  <hmdb-id>HMDB29464</hmdb-id>
  <chembl-id nil="true"/>
  <chemspider-id nil="true"/>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference nil="true"/>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002717</chemdb-id>
  <dsstox-id nil="true"/>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00121693</susdat-id>
  <iupac>6-[(1E,3E,5E)-6-{5-ethyl-3,4-dihydroxy-3a,4-dimethyl-hexahydrofuro[2,3-b]furan-2-yl}hexa-1,3,5-trien-1-yl]-4-methoxy-5-methyl-2H-pyran-2-one</iupac>
</compound>
