3795 Fusaric Acid Fusaric acid is a mycotoxin found in various Fusarium species such as Fusarium moniliforme. It has been proposed for a various therapeutic applications but is primarily used as a research tool. Fusaric acid is moderately toxic and can be found in contaminated corn and cereal grains including barley, wheat, millets and sorghum. (L1963, A3020) 536-69-6 3442 C10H13NO2 White powder. Oral, dermal, inhalation, and parenteral (contaminated drugs). (A3101) Fusaric acid affects neurotransmitter levels by acting as a partial inhibitor on tyrosine-hydroxylase and an inhibitor on dopamine-beta-hydroxylase. This has been shown to cause elevated serotonin, 5-hydroxyindoleacetic acid, tyrosine, and dopamine levels in the brain, as well as decreased norepinephrine levels. These changes in neurotransmitter levels may be responsible for effects such as hypotension, altered behavior and locomotive activity, neurological disorders, and developmental problems. (A3020, A3021, A3022, A3023) No indication of carcinogenicity to humans (not listed by IARC). Fusaric acid is a mycotoxin found in various Fusarium species such as Fusarium moniliforme. It has been proposed for a various therapeutic applications but is primarily used as a research tool. Fusaric acid can be found in contaminated corn and cereal grains including barley, wheat, millets and sorghum. (L1963, A3020) Fusaric acid can contribute to mycotic keratitis infections. It also has developmental and neurological effects. (A3021, A3023) Fusaric acid can cause vomiting, hypotension, and alterations in behavioral and locomotive activity. (A3020, A3022, A3023) Natamycin ophthalmic suspension is the drug of choice for filamentous fungal infections such as mycotic keratitis. (L1964) 2010-05-07T21:39:01Z 2026-03-31T20:50:42Z http://en.wikipedia.org/wiki/Fusaric_acid C10146 true CCCCC1=CN=C(C=C1)C(O)=O C10H13NO2 InChI=1S/C10H13NO2/c1-2-3-4-8-5-6-9(10(12)13)11-7-8/h5-7H,2-4H2,1H3,(H,12,13) DGMPVYSXXIOGJY-UHFFFAOYSA-N 179.2157 179.094628665 Exogenous Solid CHEMBL24510 3324 CHEM002709 DTXSID5023085 NS00011724 5-butylpyridine-2-carboxylic acid