3673 Ammonium lauryl sulfate Ammonium lauryl sulfate (ALS) is the common name for ammonium dodecyl sulfate. ALS is classified as an alkyl sulfate and is an anionic surfactant found primarily in shampoos and body-wash as a foaming agent. Lauryl sulfates are very high-foam surfactants that disrupt the surface tension of water by forming micelles around the polar water molecules. (L1891) 2235-54-3 15610387 C12H29NO4S 283.43 Clear liquid. Oral (L1891) ; inhalation (L1891) ; dermal (L1891) While ammonium lauryl sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880) Nitrosamines can enter the body via ingestion, inhalation, or dermal contact. Once in the body, nitrosamines are metabolized by cytochrome P-450 enzymes, which essentially activates them into carcinogens. (A2878, A2879) Not listed by IARC. Certain nitrosamines are classified by IARC as either probably or possibly carcinogenic to humans (Groups 2A and 2B, respectively). (L135) Ammonium lauryl sulfate (ALS) is an anionic surfactant found primarily in shampoos and body-wash as a foaming agent. (L1891) In high concentrations ALS may cause severe irritation to eyes and skin. Inhalation and ingestion may also cause irritation. ALS may react to produce nitrosamines, which are believed to be carcinogenic. (L1890, L1891) In high concentrations ALS may cause severe irritation to eyes and skin. Inhalation and ingestion may also cause irritation. (L1891) 2009-11-19T02:56:58Z 2026-04-17T16:06:16Z http://en.wikipedia.org/wiki/Ammonium_lauryl_sulfate 53474 true Cytochrome P450 2A1 (P11711) Cytochrome P450 2A6 (P11509) Cytochrome P450 2E1 (P05181) NAD(P)H dehydrogenase [quinone] 1 (P15559) (A2878, A2879) N.CCCCCCCCCCCCOS(O)(=O)=O C12H29NO4S InChI=1S/C12H26O4S.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);1H3 BTBJBAZGXNKLQC-UHFFFAOYSA-N 283.428 283.181729111 Exogenous Liquid CHEM002593 NS00082878 (dodecyloxy)sulfonic acid amine