3470 T3D3428 Pentane Pentane is found in alcoholic beverages. Pentane is present in hop oil.Pentane is any or one of the organic compounds with the formula C5H12. This alkane is a component of some fuels and is employed as a specialty solvent in the laboratory. Its properties are very similar to those of butane and hexane. It exists in three structural isomers, the branched isomers are called isopentane and neopentane. Pentane is one of the primary blowing agents used in the production of polystyrene foam. Pentane has been shown to exhibit radical scavenger function (A7839). Pentane belongs to the family of Acyclic Alkanes. These are acyclic hydrocarbons consisting only of n carbon atoms and m hydrogen atoms where m=2*n + 2. 109-66-0 8003 C5H12 72.093900 Colorless liquid. -129°C 36.1°C (97°F) 0.038 mg/mL at 25°C Oral (T29) ; inhalation (T29) ; dermal (T29) Pentane is a central nervous system depressant. It affects the peripheral nervous system through demyelinization and axonal degeneration. (T29) Pentane is absorbed following inhalation and ingestion, and to a small extent from dermal exposure. Once in the body it distributes to the tissues and blood, with the highest concentration in the adipose tissue. Pentane is metabolized by the cytochrome P-450 system. The main metabolite is 2-pentanol, followed by 3-pentanol, and 2-pentanone. These intermediates are further metabolized to glucuronic acid conjugates or oxidized to ketone products, which are excreted in the urine and expired air. (A600) LD50: 446 mg/kg (Intravenous, Mouse) (T14) LC50: 364 g/m3 over 4 hours (Inhalation, Rat) (T14) Pentane is found in gasoline, which is possibly carcinogenic to humans (Group 2B). (L135) Pentanes are components of some fuels, such as gasoline, and are also used as specialty solvents in the laboratory. (L1287) Pentane is a central nervous system depressant and can cause loss of consciousness and coma at high doses. Ingestion may cause pulmonary toxicity due to pentane aspiration, including chemical pneumonitis, acute lung injury, and hemorrhage. Cardiovascular effects may include ventricular dysrhythmias and sudden death. (T29, A600) Pentane is a central nervous system depressant and can cause anorexia, euphoria, dizziness, headache, depression, confusion, inability to concentrate, anoxia, narcosis, and loss of consciousness and coma at high concentrations. Contact with the skin results in cause drying, erythema, hyperpigmentation, hyperemia, dermatitis, burning pain, and blisters. (T14, T29, A600) Treatment is mainly symptomatic and supportive. Gastric lavage, emesis, and the administration of activated charcoal should be avoided, as vomiting increases the risk of aspiration. (A600) 2009-07-30T17:58:13Z 2026-03-31T16:59:19Z http://en.wikipedia.org/wiki/Pentane C00489 37830 CPD-285 n-Pentane DB03119 LNK 3520 true CCCCC C5H12 InChI=1S/C5H12/c1-3-5-4-2/h3-5H2,1-2H3 OFBQJSOFQDEBGM-UHFFFAOYSA-N 72.1488 72.093900384 Exogenous Liquid 3.39 HMDB29603 CHEMBL16102 7712 <p>Franz J. Broecker, Karl G. Baur, Rolf Platz, Joachim Stabenow, &#8220;Preparation of 2-methyl-pentane-2,4-diol.&#8221; U.S. Patent US4298766, issued March, 1970.</p> CHEM002457 DTXSID2025846 NS00008602 0.0 24.8072 10.266676947682711 2 0 0 0 0 3.41 -2.54 2.10e-01 g/l