<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">3468</id>
  <title>T3D3426</title>
  <common-name>n-Butane</common-name>
  <description>n-Butane is a hydrocarbon and one of two isomers of butane. Butanes are highly flammable, colorless, odorless, easily liquefied gases. They are components of gasoline and can also be used as refrigerants and propellants in aerosol sprays. Butane gas is sold bottled as a fuel for cooking and camping and is also found in cigarette lighters. Butane is a simple asphyxiant and commonly used substance of abuse that is responsible for a large number of "solvent related" deaths. (L1283, L1284)</description>
  <cas>106-97-8</cas>
  <pubchem-id>7843</pubchem-id>
  <chemical-formula>C4H10</chemical-formula>
  <weight>58.078250</weight>
  <appearance>Colorless gas.</appearance>
  <melting-point>-138.2°C</melting-point>
  <boiling-point></boiling-point>
  <density nil="true"/>
  <solubility>0.0612 mg/mL at 25°C [MCAULIFFE,C (1966)]</solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Inhalation (L1283) </route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Butane is a simple asphyxiant and causes toxicity by displacing oxygen. It also affects the central nervous system by enhancing glycine receptors and inhibiting N-methyl-d-aspartate (NMDA) receptors. (L1284, A352)</mechanism-of-toxicity>
  <metabolism></metabolism>
  <toxicity>LC50: 658 g/m3 over 4 hours (Inhalation, Rat) (T14)</toxicity>
  <lethaldose></lethaldose>
  <carcinogenicity>n-Butane is found in gasoline, which is possibly carcinogenic to humans (Group 2B). (L135)</carcinogenicity>
  <use-source>Butanes are components of gasoline and can also be used as refrigerants and propellants in aerosol sprays. Butane gas is sold bottled as a fuel for cooking and camping and is also found in cigarette lighters. Butane is a simple asphyxiant and commonly used substance of abuse that is responsible for a large number of "solvent related" deaths. (L1283, L1284)</use-source>
  <min-risk-level></min-risk-level>
  <health-effects>Butane targets the central nervous system and cardiovascular system. Inhalation of butane can cause frostbite which can result in death from asphyxiation and ventricular fibrillation. (L1283, L1284)</health-effects>
  <symptoms>Inhalation of butane can cause euphoria, hallucinations, confusion, blurred vision, slurred speech, nausea, vomiting, coughing, sneezing, increased salivation, drowsiness, narcosis, asphyxia, cardiac arrhythmia, and frostbite. (L1283, L1284)</symptoms>
  <treatment>Treatment for butane poisoning is supportive and symptomatic. Stimulants should not be administered. Recovery normally occurs quickly once exposure has ceased but support of the cardiovascular and respiratory systems may be needed. (L1284)</treatment>
  <created-at type="dateTime">2009-07-30T17:58:12Z</created-at>
  <updated-at type="dateTime">2026-04-13T22:25:50Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>http://en.wikipedia.org/wiki/Butane</wikipedia>
  <uniprot-id></uniprot-id>
  <kegg-compound-id></kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id>37808</chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id></ctd-id>
  <stitch-id>n-Butane</stitch-id>
  <drugbank-id>DB03689</drugbank-id>
  <pdb-id></pdb-id>
  <actor-id>3481</actor-id>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>CCCC</moldb-smiles>
  <moldb-formula>C4H10</moldb-formula>
  <moldb-inchi>InChI=1S/C4H10/c1-3-4-2/h3-4H2,1-2H3</moldb-inchi>
  <moldb-inchikey>IJDNQMDRQITEOD-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">58.1222</moldb-average-mass>
  <moldb-mono-mass type="decimal">58.07825032</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Gas</state>
  <logp></logp>
  <hmdb-id></hmdb-id>
  <chembl-id>CHEMBL134702</chembl-id>
  <chemspider-id>7555</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002455</chemdb-id>
  <dsstox-id>DTXSID7024665</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id nil="true"/>
  <iupac>N-(3-{[4-(2,7-dihydro-1,2-oxazepin-4-yl)pyrimidin-2-yl]amino}-4-methylphenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide</iupac>
</compound>
