<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">3156</id>
  <title>T3D3114</title>
  <common-name>Myristicin</common-name>
  <description>Myristicin is found in anise. Myristicin is a constituent of dill, nutmeg, parsley and many other essential oils. May be responsible for psychotic effects of nutmeg at large doses Myristicin, 3-methoxy,4,5-methylendioxy-allylbenzene, is a natural organic compound present in the essential oil of nutmeg and to a lesser extent in other spices such as parsley and dill. Myristicin is a naturally occurring insecticide and acaricide with possible neurotoxic effects on dopaminergic neurons[citation needed]. It has hallucinogenic properties at doses much higher than used in cooking. Myristicin is a weak inhibitor of monoamine oxidase.Myristicin has been shown to exhibit apoptotic and hepatoprotective functions (A7836, A7837).Myristicin belongs to the family of Benzodioxoles. These are organic compounds containing a benzene ring fused to either isomers of dioxole.</description>
  <cas>607-91-0</cas>
  <pubchem-id>4276</pubchem-id>
  <chemical-formula>C11H12O3</chemical-formula>
  <weight>192.078640</weight>
  <appearance nil="true"/>
  <melting-point>&lt; -20°C</melting-point>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Oral (ingestion) (L1817) ; dermal (L1817)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Myristicin exerts possible neurotoxic effects on dopaminergic neurons and is a weak inhibitor of monoamine oxidase. (L1271)</mechanism-of-toxicity>
  <metabolism nil="true"/>
  <toxicity>LD50: 3000 mg/kg (Oral, Mouse) (L1272)
LD50: 340 mg/kg (Intraperitoneal, Mouse) (L1272)
LD50: 5610 mg/kg (Dermal, Rat) (L1272)
LD50: 1470 mg/kg (Subcutaneous, Mouse) (L1272)
LD50: 8000 mg/kg (Intramuscular, Mouse) (L1272)</toxicity>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Myristicin is a plant toxin found in the essential oil of nutmeg and to a lesser extent in other spices such as parsley and dill. It is a naturally occurring insecticide and acaricide. (L1271)</use-source>
  <min-risk-level nil="true"/>
  <health-effects>Myristicin has neurotoxic effects and hallucinogenic properties. (L1271)</health-effects>
  <symptoms>Myristicin produces a semi-conscious state, and may also cause euphoria, bloodshot eyes, and memory disturbances. It is also known to induce psychoactive effects such as visual distortions. (L1271)</symptoms>
  <treatment nil="true"/>
  <created-at type="dateTime">2009-07-23T18:26:23Z</created-at>
  <updated-at type="dateTime">2026-04-03T04:19:38Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>http://en.wikipedia.org/wiki/Myristicin</wikipedia>
  <uniprot-id nil="true"/>
  <kegg-compound-id>C10480</kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id nil="true"/>
  <stitch-id>Myristicin</stitch-id>
  <drugbank-id nil="true"/>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>COC1=C2OCOC2=CC(CC=C)=C1</moldb-smiles>
  <moldb-formula>C11H12O3</moldb-formula>
  <moldb-inchi>InChI=1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3</moldb-inchi>
  <moldb-inchikey>BNWJOHGLIBDBOB-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">192.2112</moldb-average-mass>
  <moldb-mono-mass type="decimal">192.07864425</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Liquid</state>
  <logp nil="true"/>
  <hmdb-id>HMDB35873</hmdb-id>
  <chembl-id>CHEMBL481044</chembl-id>
  <chemspider-id>4125</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference nil="true"/>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002443</chemdb-id>
  <dsstox-id>DTXSID1025693</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00017756</susdat-id>
  <iupac nil="true"/>
  <moldb-polar-surface-area>27.69</moldb-polar-surface-area>
  <moldb-refractivity>52.575400000000016</moldb-refractivity>
  <moldb-polarizability>20.230269076483445</moldb-polarizability>
  <moldb-rotatable-bond-count>3</moldb-rotatable-bond-count>
  <moldb-acceptor-count>3</moldb-acceptor-count>
  <moldb-donor-count>0</moldb-donor-count>
  <moldb-pka-strongest-acidic nil="true"/>
  <moldb-pka-strongest-basic>-4.538876091827281</moldb-pka-strongest-basic>
  <moldb-physiological-charge>0</moldb-physiological-charge>
  <moldb-number-of-rings>2</moldb-number-of-rings>
  <moldb-alogps-logp>2.47</moldb-alogps-logp>
  <moldb-alogps-logs>-2.37</moldb-alogps-logs>
  <moldb-alogps-solubility>8.28e-01 g/l</moldb-alogps-solubility>
</compound>
