3081 Hexobarbital Hexobarbital is only found in individuals that have used or taken this drug. It is a barbiturate that is effective as a hypnotic and sedative. [PubChem]Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. 56-29-1 3608 C12H16N2O3 236.116090 White powder. 146.5°C 435 mg/L (at 25°C) Oral Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. Hepatic. No indication of carcinogenicity to humans (not listed by IARC). For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli. They cause slurred speech, disorientation and "drunken" behavior. They are physically and psychologically addictive. They cause slurred speech, disorientation and "drunken" behavior. They are physically and psychologically addictive. Symptoms of an overdose typically include sluggishness, incoordination, difficulty in thinking, slowness of speech, faulty judgment, drowsiness or coma, shallow breathing, staggering, and in severe cases coma and death. 2009-07-21T20:28:47Z 2026-05-14T16:59:45Z Hexobarbital C11723 5706 Hexobarbital DB01355 true CN1C(=O)NC(=O)C(C)(C1=O)C1=CCCCC1 C12H16N2O3 InChI=1S/C12H16N2O3/c1-12(8-6-4-3-5-7-8)9(15)13-11(17)14(2)10(12)16/h6H,3-5,7H2,1-2H3,(H,13,15,17) UYXAWHWODHRRMR-UHFFFAOYSA-N 236.267 236.116092388 Exogenous Solid 1.98 HMDB15444 CHEMBL7728 3482 CHEM002391 DTXSID9023122 NS00004868 5-(cyclohex-1-en-1-yl)-1,5-dimethyl-1,3-diazinane-2,4,6-trione 66.48 61.947399999999995 24.135988497512763 1 3 1 7.4051085924581885 0 2 1.80 -2.19 1.51e+00 g/l