3051 Chlormezanone Chlormezanone is only found in individuals that have used or taken this drug. It is a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. [PubChem]Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways. 80-77-3 2717 C11H12ClNO3S 273.022640 White powder. 116.2-118.6°C 2500 mg/L (at 25°C) Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways. No indication of carcinogenicity to humans (not listed by IARC). Used in the management of anxiety and in the treatment of muscle spasm. Symptoms of overdose include drowsiness, weakness, nausea, dizziness, abdominal pain, cerebral oedema and renal tubular necrosis, hyperglycaemia and hypoglycaemia, liver damage, encephalopathy, coma and death. 2009-07-21T20:28:33Z 2026-03-31T17:08:35Z Chlormezanone 3619 Chlormezanone DB01178 true CN1C(C2=CC=C(Cl)C=C2)S(=O)(=O)CCC1=O C11H12ClNO3S InChI=1S/C11H12ClNO3S/c1-13-10(14)6-7-17(15,16)11(13)8-2-4-9(12)5-3-8/h2-5,11H,6-7H2,1H3 WEQAYVWKMWHEJO-UHFFFAOYSA-N 273.736 273.022641652 Exogenous Solid 1.3 HMDB15309 CHEMBL1200714 2616 CHEM002366 DTXSID3022798 NS00008711 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione