2966 Methdilazine Methdilazine is only found in individuals that have used or taken this drug. It is a phenothiazine compound with antihistaminic activity. It is used in the treatment of various dermatoses to relieve pruritus.Methdilazine binds to the histamine H₁ receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. 1982-37-2 14677 C18H20N2S 296.134720 White powder. 87-88°C 0.348 mg/L Well absorbed in the digestive tract. Methdilazine binds to the histamine H₁ receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. No indication of carcinogenicity to humans (not listed by IARC). Used for the symptomatic relief of hypersensitivity reactions and particularly for the control of pruritic skin disorders Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands, and trouble in sleeping. 2009-07-21T20:27:54Z 2026-04-03T16:52:18Z Methdilazine C07175 774910 Methdilazine DB00902 true CN1CCC(CN2C3=CC=CC=C3SC3=CC=CC=C23)C1 C18H20N2S InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20/h2-9,14H,10-13H2,1H3 HTMIBDQKFHUPSX-UHFFFAOYSA-N 296.43 296.13471934 Exogenous Solid 5.23 HMDB15038 CHEMBL1200959 14009 CHEM002296 DTXSID6023282 NS00026450 10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine