<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">2571</id>
  <title>T3D2530</title>
  <common-name>Epibatidine</common-name>
  <description>Epibatidine is a toxin found in certain poisonous frogs (Epipedobates tricolour). It is a  powerful analgesic and works by activating nicotinic acetylcholine receptors. (L1074)</description>
  <cas>140111-52-0</cas>
  <pubchem-id>1204</pubchem-id>
  <chemical-formula>C11H13ClN2</chemical-formula>
  <weight>208.076730</weight>
  <appearance>White powder.</appearance>
  <melting-point></melting-point>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Injection (sting/bite)  (A2835) ; inhalation (smoking) (L1810)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074)</mechanism-of-toxicity>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Epibatidine is a toxin found in certain poisonous frogs (Epipedobates tricolour). (L1074)</use-source>
  <min-risk-level nil="true"/>
  <health-effects>Epibatidine is neurotoxic. It may also cause receptor blocks at neuromuscular junctions, causing respiratory paralysis and death. It is also a powerful analgesic. (L1074)</health-effects>
  <symptoms>Epibatidine is neurotoxic. It may also cause receptor blocks at neuromuscular junctions, causing respiratory paralysis and death. It is also a powerful analgesic. (L1074)</symptoms>
  <treatment nil="true"/>
  <created-at type="dateTime">2009-07-03T22:19:13Z</created-at>
  <updated-at type="dateTime">2026-04-05T10:56:13Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia nil="true"/>
  <uniprot-id nil="true"/>
  <kegg-compound-id>C11690</kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id>C082748</ctd-id>
  <stitch-id>Epibatidine</stitch-id>
  <drugbank-id>DB07720</drugbank-id>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>ClC1=CC=C(C=N1)C1CC2CCC1N2</moldb-smiles>
  <moldb-formula>C11H13ClN2</moldb-formula>
  <moldb-inchi>InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2</moldb-inchi>
  <moldb-inchikey>NLPRAJRHRHZCQQ-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">208.687</moldb-average-mass>
  <moldb-mono-mass type="decimal">208.076726133</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp nil="true"/>
  <hmdb-id nil="true"/>
  <chembl-id>CHEMBL6623</chembl-id>
  <chemspider-id>1167</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference>&lt;p&gt;Csaba Sz antay, Zsuzsanna B. Kardos, Istv an Moldvai, Eszter T. Major, Csaba Sz antay, Jr., Attila M andi, G abor Blask o, Gyula Simig, Gy orgyi Lax, S andor Drabant, Tamas Sz all asi, M arton Fekete, G abor Gigler, &amp;#8220;Process for the preparation of epibatidine.&amp;#8221; U.S. Patent US5545741, issued March, 1994.&lt;/p&gt;</synthesis-reference>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002072</chemdb-id>
  <dsstox-id>DTXSID00894067</dsstox-id>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id>NS00068280</susdat-id>
  <iupac>2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane</iupac>
</compound>
