<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">2493</id>
  <title>T3D2453</title>
  <common-name>Gyromitrin</common-name>
  <description>Gyromitrin is found in mushrooms. Toxin from the fungus Gyromitra esculenta. Freq. cause of mushroom poisoning Gyromitrin is a toxin and possible carcinogen present in most members of the fungal genus Gyromitra, most notably the false morel G. esculenta.</description>
  <cas>16568-02-8</cas>
  <pubchem-id>5365327</pubchem-id>
  <chemical-formula>C4H8N2O</chemical-formula>
  <weight>100.063660</weight>
  <appearance nil="true"/>
  <melting-point>19.5°C</melting-point>
  <boiling-point>143 °C, 416°K, 289 °F</boiling-point>
  <density></density>
  <solubility></solubility>
  <specific-gravity></specific-gravity>
  <flash-point></flash-point>
  <vapour-pressure></vapour-pressure>
  <route-of-exposure>Oral, dermal, inhalation, and parenteral (contaminated drugs). (A3101)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>The toxicity is caused by the conversion of the hydrazine (gyromitrin) to a hydrazine metabolite intermediate monomethylhydrazine. This occurs when gyromitrin begins to be metabolized and it undergoes hydrolysis. The necrosis and steatosis are caused by monomethylhydrazine. (L1013)</mechanism-of-toxicity>
  <metabolism>Gyromitrin is converted to a hydrazine metabolite intermediate monomethylhydrazine. This occurs when gyromitrin begins to be metabolized and it undergoes hydrolysis. (L1013)</metabolism>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>3, not classifiable as to its carcinogenicity to humans. (L135)</carcinogenicity>
  <use-source>Gyromitrin is a toxic and possibly carcinogenic chemical present in most members of the fungal genus Gyromitra, most notably the false morel G. esculenta. (L1013)</use-source>
  <min-risk-level nil="true"/>
  <health-effects>Consuming large amounts of gyromitrin, such as are found in untreated false morels, may lead to catastrophic liver failure and death. (L1013)</health-effects>
  <symptoms>Initial symptoms of gyromitrin exposure include headache, nausea and dizziness. As gyromitrin is quite volatile, even just the presence of false morels in a poorly ventilated space may be enough to cause these symptoms. (L1013)</symptoms>
  <treatment nil="true"/>
  <created-at type="dateTime">2009-07-03T20:54:23Z</created-at>
  <updated-at type="dateTime">2016-11-09T01:08:40Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia>http://en.wikipedia.org/wiki/Gyromitrin</wikipedia>
  <uniprot-id nil="true"/>
  <kegg-compound-id>C08305</kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id>5583</chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id>C005666</ctd-id>
  <stitch-id>Gyromitrin </stitch-id>
  <drugbank-id nil="true"/>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>[H]\C(C)=N/N(C)C=O</moldb-smiles>
  <moldb-formula>C4H8N2O</moldb-formula>
  <moldb-inchi>InChI=1S/C4H8N2O/c1-3-5-6(2)4-7/h3-4H,1-2H3/b5-3+</moldb-inchi>
  <moldb-inchikey>IMAGWKUTFZRWSB-HWKANZROSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">100.1191</moldb-average-mass>
  <moldb-mono-mass type="decimal">100.063662888</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Liquid</state>
  <logp nil="true"/>
  <hmdb-id>HMDB33952</hmdb-id>
  <chembl-id nil="true"/>
  <chemspider-id>19957776</chemspider-id>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference nil="true"/>
  <structure-image-caption nil="true"/>
  <chemdb-id>CHEM002042</chemdb-id>
  <dsstox-id nil="true"/>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id nil="true"/>
  <iupac>N'-[(1E)-ethylidene]-N-methylformohydrazide</iupac>
</compound>
