1108 Barium ferrate Barium ferrate is a chemical compound of barium and iron. Barium is a metallic alkaline earth metal with the symbol Ba, and atomic number 56. It never occurs in nature in its pure form due to its reactivity with air, but combines with other chemicals such as sulfur or carbon and oxygen to form barium compounds that may be found as minerals. (L214, 408) 13773-23-4 95019 C8H10AsNO4 258.982580 White powder. Oral (L214) ; inhalation (L214) Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to intracellular compartments. The intracellular translocation of potassium results in a decreased resting membrane potential, making the muscle fibers electrically unexcitable and causing paralysis. Some of these barium's effects may also be due to barium induced neuromuscular blockade and membrane depolarization. (L214) Barium compounds are absorbed via ingestion and inhalation, the extent of which depends on the individual compound. In the body, the majority of the barium is found in the bone, while small amounts exists in the muscle, adipose, skin, and connective tissue. Barium is not metabolized in the body, but it may be transported or incorporated into complexes or tissues. Barium is excreted in the urine and faeces. (L214) 1 to 15 grams for an adult human (barium salts). (T48) 3, not classifiable as to its carcinogenicity to humans. (L135) Intermediate Oral: 0.2 mg/kg/day (L134) Chronic Oral: 0.2 mg/kg/day (L134) The health effects of the different barium compounds depend on how well the compound dissolves in water or the stomach contents. At low doses, barium acts as a muscle stimulant, while higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea, paralysisand possibly death. Barium may also cause gastrointestinal disturbances, damage the kidneys and cause decreases in body weight. (L214) Ingesting excess barium may cause vomiting, abdominal cramps, diarrhea, difficulties in breathing, increased or decreased blood pressure, numbness around the face, and muscle weakness. High levels may result in changes in heart rhythm or paralysis and possibly death. (L214) Intravenous infusion of potassium often relieves many of the symptoms of barium toxicity. (L214) 2009-06-19T21:58:18Z 2026-04-05T17:42:32Z Barium ferrate true CC(=O)NC1=CC=C(C=C1)[As](O)(O)=O C8H10AsNO4 InChI=1S/C8H10AsNO4/c1-6(11)10-8-4-2-7(3-5-8)9(12,13)14/h2-5H,1H3,(H,10,11)(H2,12,13,14) LTGKKKITNWDUCD-UHFFFAOYSA-N 259.0909 258.98257923 Exogenous Solid CHEMBL1605998 85737 CHEM000944 NS00079699 (4-acetamidophenyl)arsonic acid