745 Zinc sulfate Zinc sulfate is used as a malting/fermenting aid and as a nutrient supplement Zinc sulfate (ZnSO4) is a colorless crystalline, water-soluble chemical compound. The hydrated form, ZnSO4*7H2O, the mineral goslarite, was historically known as white vitriol and can be prepared by reacting zinc with aqueous sulfuric acid. It may also be prepared by adding solid zinc to a copper(II) sulfate solution.<br /> Zinc sulfate has been shown to exhibit antibiotic and anti-spectic functions (A7766, A7767).<br /> Zinc sulfate belongs to the family of Transition Metal Sulfates. These are inorganic compounds in which the largest oxoanion is sulfate, and in which the heaviest atom not in an oxoanion is a transition metal. 7733-02-0 24424 O4SZn 159.880880 White powder. 680°C (decomp, anhydrous); 100°C (heptahydrate); 70°C (decomp, hexahydrate) 740°C Inhalation (L49) ; oral (L49) ; dermal (L49) Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49) Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49) LD50: 57 mg/kg (Oral, Mouse) (T13) LD50: 71.7 mg/kg (Intraperitoneal, Mouse) (T13) LD50: 40 mg/kg (Intravenous, Rat) (T81) 10 to 30 grams for and adult human. (T8) No indication of carcinogenicity to humans (not listed by IARC). Zinc sulfate is used in animal feeds, fertilizers, agricultural sprays, electrolytes for zinc plating, as a mordant in dyeing, as a preservative for skins and leather and in medicine as an astringent and emetic. (L79) Intermediate Oral: 0.3 mg/kg/day (L134) Chronic Oral: 0.3 mg/kg/day (L134) Chronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49) Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49) Zinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49) 2009-03-27T01:47:29Z 2026-04-05T16:02:01Z Metallothionein-2 (P02795) Metallothionein-1G (P13640) Metallothionein-1H (P80294) Metallothionein-3 (P25713) Metallothionein-1F (P04733) Metallothionein-1E (P04732) Metallothionein-1X (P80297) Metallothionein-1A (P04731) Metallothionein-1B (P07438) Metallothionein-1M (Q8N339) Metallothionein-4 (P47944) Metallothionein-1L (Q93083) Cysteine-rich protein 1 (P50238) Cysteine-rich protein 2 (P52943) Cysteine-rich protein 3 (Q6Q6R5) Serum albumin (P02768) (L49, A49, L92) http://en.wikipedia.org/wiki/Zinc_sulfate 35176 D019287 Zinc sulfate 12163 true Metallothionein-2 (P02795) Metallothionein-1G (P13640) Metallothionein-1H (P80294) Metallothionein-3 (P25713) Metallothionein-1F (P04733) Metallothionein-1E (P04732) Metallothionein-1X (P80297) Metallothionein-1A (P04731) Metallothionein-1B (P07438) Metallothionein-1M (Q8N339) Metallothionein-4 (P47944) Metallothionein-1L (Q93083) Cysteine-rich protein 1 (P50238) Cysteine-rich protein 2 (P52943) Cysteine-rich protein 3 (Q6Q6R5) Serum albumin (P02768) (L49, A49, L92) [Zn++].[O-]S([O-])(=O)=O O4SZn InChI=1S/H2O4S.Zn/c1-5(2,3)4;/h(H2,1,2,3,4);/q;+2/p-2 NWONKYPBYAMBJT-UHFFFAOYSA-L 161.472 159.880875756 Exogenous Solid HMDB34907 CHEMBL1200929 22833 CHEM000671 DTXSID2040315 NS00076230 zinc(2+) ion sulfate