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Record Information
Version1.0
Creation Date2016-05-19 01:31:12 UTC
Update Date2016-11-09 01:09:15 UTC
Accession NumberCHEM003978
Identification
Common NameHydrazine, methyl-
ClassSmall Molecule
DescriptionMethylhydrazines are hydrazines that have additional methyl groups.
Contaminant Sources
  • Clean Air Act Chemicals
  • HPV EPA Chemicals
  • OSHA Hazardous Chemicals
  • STOFF IDENT Compounds
Contaminant TypeNot Available
Chemical Structure
Thumb
Synonyms
ValueSource
Methyl-hydrazineChEMBL
Chemical FormulaCH6N2
Average Molecular Mass46.073 g/mol
Monoisotopic Mass46.053 g/mol
CAS Registry Number60-34-4
IUPAC Namemethylhydrazine
Traditional Namemethyl hydrazine
SMILESCNN
InChI IdentifierInChI=1S/CH6N2/c1-3-2/h3H,2H2,1H3
InChI KeyHDZGCSFEDULWCS-UHFFFAOYSA-N
Chemical Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as hydrazines and derivatives. These are compounds comprising the hydrazine functional group, with the general formula R1R2NNR3R4.
KingdomOrganic compounds
Super ClassOrganonitrogen compounds
ClassHydrazines and derivatives
Sub ClassNot Available
Direct ParentHydrazines and derivatives
Alternative Parents
Substituents
  • Hydrocarbon derivative
  • Hydrazine derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External DescriptorsNot Available
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
PathwaysNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility733.0 mg/mLALOGPS
logP-1.3ALOGPS
logP-0.81ChemAxon
logS1.2ALOGPS
pKa (Strongest Basic)5.75ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area38.05 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity24.9 m3·mol-1ChemAxon
Polarizability5.16 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
Toxicity Profile
Route of ExposureNot Available
Mechanism of ToxicityNot Available
MetabolismNot Available
Toxicity ValuesNot Available
Lethal DoseNot Available
Carcinogenicity (IARC Classification)Not Available
Uses/SourcesNot Available
Minimum Risk LevelNot Available
Health EffectsNot Available
SymptomsNot Available
TreatmentNot Available
Concentrations
Not Available
DrugBank IDNot Available
HMDB IDNot Available
FooDB IDNot Available
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkMethylhydrazines
Chemspider ID5837
ChEBI IDNot Available
PubChem Compound ID6061
Kegg Compound IDNot Available
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
1. Zinner,G,G, Gebhardt,U,U (1971) [Acylation of methylhydrazine]. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft;Arch Pharm Ber Dtsch Pharm Ges;1971 Sep;304(9):706-12
2. drugbank entry DB04361: DrugBank DB04361: Methylhydrazine
3. SICHER,K,K, BACKHOUSE,T W,TW (1965) EXPERIENCES WITH METHYLHYDRAZINE. British medical journal;Br Med J;1965 Mar;1(5438):858-9
4. Bollag,W,W (1968) Experimental studies with methylhydrazine derivatives. Acta geneticae medicae et gemellologiae;Acta Genet Med Gemellol (Roma);1968 Jan;17(1):158-70
5. Tu,L S,LS, Ianushevskaia,M I,MI, Smirnova,I B,IB, Graevskiĭ,E Ia,EIa (1975) [Mechanism of the radiosensitizing action of methylhydrazine]. Radiobiologiia;Radiobiologiia;1975 Sep-Oct;15(5):754-7
6. Sartoris,S,S, Bachi,C,C, Blefari,D,D, Cavallero,P,P, Vergnano,F,F, Fazio,M,M (1968) [Methylhydrazine in the treatment of Hodgkin's disease]. Minerva medica;Minerva Med.;1968 Jan;59(7):296-300
7. Finotto,E,E, Grigoletto,E,E, Fiorentino,M,M (1968) [Methylhydrazine in Hodgkin's disease in reticulosarcoma]. Il Cancro;Cancro;1968 ;21(2):165-84
8. Zangger,J,J (1967) [Cytotoxic effect by a methylhydrazine compound]. Arzneimittel-Forschung;Arzneimittelforschung;1967 Apr;17(4):511-3
9. Beltrametti,L,L, Almici,C,C (1967) [Methylhydrazine in the therapy of malignant lymphopathies]. Il Policlinico. Sezione pratica;Policlinico Prat;1967 Jan;74(3):82-5
10. Kleibel,F,F (1965) [Studies with 3H-labeled methylhydrazine derivatives]. Nuclear-Medizin;Nucl Med (Stuttg);1965 ;2:63-7